Rejuran Before and After: What This Salmon-DNA Skin Booster Really Does — A Gangnam Doctor's Honest Guide

Dr. Hyunji Kim
2026-07-018 min read

"I've seen the Rejuran before and after photos online — will my skin actually look like that?" I hear this almost every week, usually from someone holding up a phone. And I understand why: the glow-up shots are everywhere. But before-and-after images only tell half the story, and the honest half is the part I want to give you here.
I'm Dr. Hyunji Kim, director at Delphic Clinic in Gangnam. I've treated a lot of Rejuran patients — local Seoulites and travellers flying in for a few days — and I've learned exactly who lights up with this treatment and who I gently send elsewhere. Here's what Rejuran really does, what the results look like, and what it honestly can't do.
What it actually is — in plain language
Rejuran is a skin booster made from purified polynucleotides (PN) — fragments of DNA derived from salmon. That sounds dramatic, but it's simply a well-studied molecule that's remarkably compatible with human skin. Injected in tiny amounts across the face, it acts like a repair signal: it calms inflammation, supports your skin's own collagen and elastin production, and improves the underlying quality of the skin. Think of it less as 'filling' and more as 'healing and rebuilding' the fabric of your skin.

Here's the honest part: Rejuran is not a filler. It won't build a cheek, sharpen a jawline, or lift sagging skin. It doesn't add volume where you've lost it. What it does is make the skin itself healthier — smoother texture, softer fine lines, better elasticity, more even tone. If you were expecting a dramatic overnight transformation, Rejuran will disappoint you. If you want your own skin to genuinely improve, it's one of the treatments I trust most.
Who it's really for
Rejuran shines for people who want their skin to look better in a real, unfiltered way. In my chair, these are the patients who consistently love their before and after:
- People in their late 20s to 50s noticing crepey texture, dullness, or early fine lines.
- Those with tired, thin, or dehydrated skin that no cream seems to fix.
- Patients with fine under-eye lines and thin under-eye skin (with Rejuran I).
- Anyone with acne-scar texture or enlarged pores wanting smoother skin quality.
- Travellers who want a subtle 'my skin but better' glow with minimal downtime before a trip or event.
And who I steer elsewhere: if your main concern is sagging or jowls, I'll talk to you about lifting options — not Rejuran. If you've lost facial volume, filler is the honest answer. If you want an instant dramatic change for a wedding next week, Rejuran's gradual timeline won't suit you. I'd rather send you to the right treatment than sell you the wrong one.
How it compares — an honest comparison
Rejuran often gets lumped in with other skin boosters, but they solve different problems. Here's how I explain it to patients deciding between them:
In practice these aren't rivals — I often combine Rejuran with a hydrating booster or filler for a fuller result. The point is matching the tool to your actual concern.
Before and after: what's realistic
Here's the truth about Rejuran before and after: it's a slow reveal, not a switch. In the first week or two you may notice hydration and a slight glow. The meaningful change — smoother texture, softer fine lines, skin that looks less tired — builds over 4 to 8 weeks as your own collagen responds. After a full course, patients often say their skin simply looks 'healthier' in a way that's hard to point to but easy to feel. It rarely looks 'done' — that's exactly why I like it.

Get a free 1:1 consultation
Message our English-speaking team — same price as locals, no pressure.
What to expect — step by step
- 1
1. Free consultation
We look at your skin closely, discuss your concerns and goals, and confirm whether Rejuran — and which type — actually fits. If it doesn't, I'll say so.
- 2
2. Numbing & prep
We cleanse the skin and apply numbing cream for about 20–30 minutes so the session is comfortable.
- 3
3. The session
I inject small amounts of Rejuran across the treatment area using fine needles. It takes around 15–20 minutes.
- 4
4. Back to your day
You may have tiny bumps and mild redness for a few hours to a day. Most patients head straight back out; makeup is fine by the next morning.
- 5
5. Results build over weeks
Your skin quality improves gradually over 4–8 weeks. We space sessions 2–4 weeks apart and plan maintenance from there.
How we do it at Delphic — and why it matters
Rejuran is doctor-administered at Delphic — I decide the type, depth and pattern based on your skin, not a fixed template. We use genuine Rejuran product, and I'm honest about how many sessions you'll realistically need so you can plan (and budget) properly. If you're visiting Seoul for a short time, we'll design a schedule that actually works around your trip rather than overpromising.

Dr. Kim was so honest — she actually talked me out of one thing I asked for and recommended Rejuran instead. My skin looks calmer and smoother weeks later. The English interpreter made everything easy as a visitor.
How much does it cost in Korea?
Rejuran pricing depends on the type and volume. There are a few versions — Healer (all-round skin repair), I (delicate under-eye area), HB (with hyaluronic acid for hydration) and S (for scars and firmer areas). Here are our genuine prices:
| Rejuran Healer 2cc | ₩350,000$250 |
| Rejuran I 1cc | ₩250,000$180 |
| Rejuran HB 1cc | ₩300,000$220 |
| Rejuran S 1cc | ₩300,000$220 |
Coming from overseas? Here's how we make it easy
We're a one-minute walk from Sinnonhyeon Station Exit 3, with on-site English and Chinese interpreters so nothing gets lost in translation. Rejuran is one-day-friendly — you can consult and treat in a single visit with minimal downtime, which makes it ideal for a Seoul trip. And you pay exactly the same price as a local patient.
Start with a free 1:1 consultation
Before anything, we talk. The consultation is free, there's no pressure, and my job is to tell you honestly whether Rejuran is right for you — or whether something else would serve your skin better. If it's not for you, I'll say so.
Get a free 1:1 consultation
Message our English-speaking team — same price as locals, no pressure.
Rejuran won't remake your face — but for genuinely healthier, smoother, more resilient skin, it's one of the treatments I trust most. Come in, let's look at your skin together, and I'll give you the honest plan. — Dr. Hyunji Kim, Delphic Clinic, Gangnam, Seoul.
Frequently asked questions
Does Rejuran hurt?
There's a small sting with each injection because Rejuran is placed with fine microneedle points across the skin. We apply numbing cream for 20–30 minutes first, and most patients rate it a mild, tolerable discomfort — more 'annoying' than painful. Sensitive areas like under the eyes feel a bit more. It's over quickly.
How long does Rejuran last?
Rejuran works by repairing skin quality over time, so results build for 4–8 weeks and then hold. After a full course of 3–4 sessions spaced 2–4 weeks apart, most people enjoy improved texture and elasticity for around 6–12 months, then top up. It's maintenance, not a one-and-done.
How does Rejuran compare to Skinbooster (Juvederm Volite) or Profhilo?
Roughly: Rejuran focuses on repairing skin quality and stimulating your own collagen (great for texture, fine lines, resilience). Hyaluronic skinboosters focus more on deep hydration and glow. Profhilo remodels laxity with big HA molecules. They overlap and are often combined — the right pick depends on your main concern.
Is there downtime with Rejuran?
Minimal. You may see tiny injection bumps and some redness for a few hours to a day, and occasional small bruises. Most people go back to their day, and makeup is fine by the next morning. It's a genuinely one-day-friendly treatment.
How many Rejuran sessions do I need?
Most patients need a starter course of 3–4 sessions, 2–4 weeks apart, to see meaningful before-and-after change. Then one maintenance session every few months. Someone with early skin ageing may need fewer; more damaged or acne-scarred skin may need more.
How much does Rejuran cost in Korea?
See the prices in the article. Rejuran Healer 2cc is ₩350,000, Rejuran I 1cc ₩250,000, Rejuran HB 1cc ₩300,000 and Rejuran S 1cc ₩300,000 — same price for locals and visitors, no foreigner mark-up.

Written by
Dr. Hyunji Kim
Dr. Hyunji Kim is the director and lead physician at Delphic Clinic in Gangnam, Seoul. She trained at Korea University Medical Center and personally performs consultations and procedures for both local and international patients.
